SUBJECT: SLEEP -Notes from Roc Nutrition Investigator
Sleep allows your brain to be washed – My interest in sleep research began in the 1980s, but it was not until October 11 and 18 this year that it has been found why it is necessary. Mental fatigue, poor decision-making, impaired learning, and a heightened risk of migraine and epileptic attacks ensue when we are sleep deprived—and chronic and complete insomnia ultimately lead to death in humans, rats, and flies alike. During sleep, waste products of brain metabolism are removed from the interstitial space among brain cells where they accumulate. Sleep, therefore, might be required for potentially toxic metabolites—the very results of a working brain—to be cleared from the tissue. The interstitial space in the waking mouse brain is only 14% of brain volume, but increases by over 60% in natural sleep. The consequence is remarkable: The flow of CSF through the interstitial space is reduced during waking to only 5% of the flow found in sleep. Science 18 October 2013: 342: 316-317
MORE ON SLEEP – 2025
Google Scholar for “shortened sleep longevity dementia”:
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C38&q=shortened+sleep+longevity+dementia&btnG=
And this review article:
“Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies.” Cappuccio et al., European Heart Journal, Volume 32, Issue 12, June 2011, Pages 1484–1492,
“Both short and long duration of sleep are predictors, or markers, of cardiovascular outcomes.”
https://academic.oup.com/eurheartj/article-abstract/32/12/1484/502022
And this quote from Wikipedia:
“On the basis of these findings, they hypothesized that the restorative properties of sleep may be linked to increased glymphatic clearance of metabolic waste products produced by neural activity in the awake brain.”
https://en.wikipedia.org/wiki/Glymphatic_system
And this one:
https://en.wikipedia.org/wiki/Health#Sleep
“In one study, people with chronic insufficient sleep, set as six hours of sleep a night or less, were found to be four times more likely to catch a cold compared to those who reported sleeping for seven hours or more a night.”
On that same topic,
“Short sleep duration of less than seven hours is correlated with coronary heart disease and increased risk of death from coronary heart disease. Sleep duration greater than nine hours is also correlated with coronary heart disease, as well as stroke and cardiovascular events.”
https://en.wikipedia.org/wiki/Sleep#Sleep_health
*To review the disclaimer. *To ask Nutrition Investigator (Roc) a question.
-Nutrition Investigator, Roc
Professor, Biochemistry, Beloit College
