Metformin
2023 paper on Metformin. It appears that metformin is not beneficial to longevity!! Questionable long term effects shown. Using the full twenty-year period, we found that type 2 diabetes patients treated with metformin had shorter survival time than matched controls, as did sulphonylurea patients.
Similar results that no help for longevity.
2018 – Metformin as a Tool to Target Aging – www.TheAntiAgingDoctor.com – He advises us that metformin is a drug that should be taken constantly, and twice a day in order to obtain the optimal benefit. The TAME study is at 850mg, twice a day I believe. That being said, adequate hydration, hepatic and renal function are critical parameters that must be carefully maintained. This is a serious medication, with serious side-effects, some of which can be fatal. It should not to be self-medicated by amateurs. That means it must be instituted and adequately supervised by a qualified endocrinologist physician who has the appropriate knowledge of the parameters of this drug, and, even more importantly, who has a high level of experience with the use of this drug. He does not agree with the misinformation that metformin inhibits, or interferes with muscle growth and development. He has not experienced that personally, nor has he ever seen that happen with any of his patients.
