Here is a spreadsheet of all the supplements I think are worth taking, and the particular diseases and conditions they are likely to have effects beneficial to your healthspan.

supplements heart disease dementias osteoarthritis energy cancer menopause sarcopenia macular degeneration weight loss diabetes
memory
alpha-keto-glutaric acid x
AREDs x
Astaxanthin x x x x x
Berberine
beta-hydroxybutyric acid x x
CoQ10
Ellagic acid x x x
Fish Oil x x
Genistein x x x
Leucine x
Melatonin x x x
Mito-C x x x x x
Olive oil
Red grape juice x
Resveratrol x x
SAMe x x x
Spermidine x x x x
Spirulina x x
Taurine x x
Tocotrienols x x x
Triumph
Vit B3, Niacin x x
Vitamin B12 x x
Vitamin D x x
Yogurt/Kefir x