In the U.S., serrapeptase is classified as a dietary supplement. Serrapeptase is used for conditions such as back pain, osteoarthritis, and rheumatoid arthritis, and for conditions generally associated with pain and swelling (inflammation), but there is no good evidence to support these uses.

Serrapeptase helps the body break down protein. This might help decrease inflammation and mucous.

NIH article 2020 “Serratiopeptidase is a proteolytic enzyme having immense applications in therapeutic areas which have been validated by several in vitro, in vivo, and clinical studies as well as through anecdotal evidences. These applications are attributable to its versatile properties including anti-inflammatory, anti-biofilm, analgesic, anti-edemic, and fibrinolytic effects. The significant impact of serratiopeptidase reported needs to be backed by more scientific data. This review encompasses the details of therapeutic applications of serratiopeptidase based on available in vitro, in vivo, and clinical studies. We found some strong evidences regarding the efficacy of serratiopeptidase. However data on safety, tolerability, and its mechanism of action need detailing. ”

RISKS: Serrapeptase can cause pneumonitis (lung inflammation) in elderly adults. This happens due to a sudden drop in white blood cells. Some common side effects after taking Serrapeptase are nausea, stomach upset, vomiting, cough, poor appetite, blood clotting disturbances, muscle & joint pain, skin reactions and rashes.