Skip to main content

SUBJ: Neuroinflammation in the pathogenesis of AD

SUBtitle: coffee and tea- they reduce inflammation

See past newsletters here

SHORT NOTES: Neuroinflammation has been identified as the third core characteristic crucial in the pathogenesis of AD;  Multimorbidity (people with multiple health conditions) is a principal cause of polypharmacy, which lead to many negative consequences such as an increased risk of adverse drug events; 7 HEART RISK FACTOR REDUCTIONS: MOTIVATION to change behavior; WebMD-build a better butt; benefits of coffee and tea- they reduce inflammation; He used genome sequencing to find her best treatment, is now cancer free at the age of 72; a robotic stocking for treating lymphatic and venous leg diseases.

LONG NOTES:

Neuroinflammation has been identified as the third core characteristic crucial in the pathogenesis of AD. More and more evidence from laboratory and clinical studies have suggested that anti-inflammatory treatments could defer or prevent the occurrence of AD.

Multimorbidity (people with multiple health conditions) is a principal cause of polypharmacy, which lead to many negative consequences such as an increased risk of adverse drug events (ADEs).3 In addition, as some studies added, having polypharmacy may contribute to the development of depression.

Heartline clinical trial: 7 HEART RISK FACTOR REDUCTIONS: blood pressure (diet, exercise, sleep), cholesterol (transfats, exercise, statins), blood sugar (diet, exercise, weight), exercise (walk more, strength training 2xweek, add intensity, stand up hourly), diet (limit sweetened beverages, sodium, processed meat, carbs, white foods, transfats), lose weight, stop smoking; why be heart healthy-full active life, independent, take care of family, feel better, more energy, in control; MOTIVATION: extrinsic (outside of you-approval, praise, money, etc), intrinsic(more important and lasting, meaningful, interesting-vary activities, add mini-goals, note small benefits)

WebMD-build a better butt- Slowly lower the hips as if sitting way back in a chair, trying to keep your knees from moving forward toward toes; then return to standing. Keep your torso tight and back straight, Forward Lunge, Backward Lunge, Side Lunge, On the Ball: Leg Lift, On the Ball: Hip Lift, Floor Work: Bridge, Side Leg Raises, Dog at a fire hydrant, Mountain Climbers, For a no-fuss butt workout, all you have to do is walk.

WebMD-benefits of coffee and tea-they have antioxidants, reduce diabetes, liver disease, stroke,  cancer, Alzheimer’s, gallstones, weight gain, and Parkinson’s risk,  people who drank 3 to 5 cups of coffee a day were less likely to have a buildup of calcium in the vessels that bring blood to your heart, they reduce inflammation.

A doctor was diagnosed with cervical, ovarian, and thyroid cancer with six-months to live. He used genome sequencing to find her best treatment. Dr Berry is now cancer free and at the age of 72 is Google Cloud’s Director of Technology.

Seen here previously, a robotic stocking for treating lymphatic and venous leg diseases is being tested and shows a 5-fold improvement in leg volume reduction, compared to the hospital’s standard compression bandages.

Story of a passionate life

(Tale of Roc’s marriage written for my 50th [now 52nd due to COVID] Carleton College Reunion)