IVERMECTIN

Ivermectin is a drug that has been considered as an additional therapy to standard treatments for cancer.  While not yet FDA approved, it is of interest.  Here is a brief set of notes on articles.  It is definitely worth discussing with a physician who is knowledgeable about ivermectin.

some studies have explored the use of ivermectin in relation to cancer. There are no studies demonstrating the drug cures cancer in humans, experts say, but some are researching the use of ivermectin in combination with other therapies to treat breast cancer.

2023 – Nurs Rep. 2023 Mar; 13(1): 315–326. Published online 2023 Feb 22. doi: 10.3390/nursrep13010030

We identify that the interviewed not only use ivermectin as anticancer treatment, but it is also used as a treatment against other diseases. Although the participants’ opinions indicate that they feel improvements in their health after the third dose, the specialist considers that there is no authorization to prescribe these alternative treatments. In addition, they confirmed that currently, there is no scientific knowledge about the application of these treatments in humans and they do not recommend their application. Thus, the anticancer mechanism of ivermectin remains to be further investigated.

The main findings show that 19% of the participants diagnosed with cancer take medicines based on ivermectin as alternative therapy to the cancer control and treatment without leaving treatment such as chemotherapy, radiotherapy, or immunotherapy, while 81% use it to treat other diseases.

Although the participants’ opinions indicate that they feel improvements in their health after the third dose, the specialist considers that there is no authorization to prescribe these alternative treatments.

2023 – Ivermectin, as an old anti-parasite drug, can suppress almost completely the growth of various human cancer (cell lines), including ovarian cancer (OC).  However, its anticancer mechanism remained to be further studied at the molecular levels. Ivermectin-related molecule-panel changes will serve a useful tool for its personalized drug therapy and prognostic assessment in OCs.

2021 – Ivermectin, a potential anticancer drug derived from an antiparasitic drug. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance and exerts the optimal effect when used in combination with other chemotherapy drugs.

2020 – Ivermectin, a dihydro derivative of avermectin (AVM), was introduced into the veterinary, agricultural and aquaculture markets for animal health in 1981. Ivermectin was soon adopted in 1987 as a human medicine that was originally used for the treatment of onchocerciasis, a parasitic infection. Since then, ivermectin has also been used to control other human diseases and has exerted a significant effect on human health and welfare. In the past decade, many published studies have attempted to determine the role of ivermectin in cancer.  ivermectin induces the multidrug resistance protein (MDR), has potent anti-mitotic activity, targets angiogenesis and inhibits cancer stem-like cells (CSCs). Many studies have proven that ivermectin exerts antitumour effects and might thus benefit patients with cancer after sufficient clinical trials.