GOUT

High fructose corn syrup elevates uric acid causing high blood pressure and gout.

2025 – apigenin exhibits protective effects against osteoporosis (OP), rheumatoid arthritis (RA), osteoarthritis (OA), gouty arthritis (GA), and intervertebral disc degeneration (IDD).

2025 Headlines from the Linus Pauling meeting: Drinking 3 to 5 cups of coffee/day is healthy! Reduces risk for cancer, CVD parkinsons, depression, cognitive function, gout, gallstone, diabetes

2025 – apigenin exhibits protective effects against osteoporosis (OP), rheumatoid arthritis (RA), osteoarthritis (OA), gouty arthritis (GA), and intervertebral disc degeneration (IDD).

2025 Headlines from the Linus Pauling meeting: Drinking 3 to 5 cups of coffee/day is healthy! Reduces risk for cancer, CVD parkinsons, depression, cognitive function, gout, gallstone, diabetes

220903notes – Gout-4% of US has gout.  the most common form of inflammatory arthritis. To diagnose gout, a doctor will do bloodwork to check your uric acid levels or take a fluid sample from the painful joint and look for urate crystals. Lifestyle changes such as losing weight, giving up alcohol and switching to a healthy diet may help prevent gout attacks. Drinking low-fat milk and eating low-fat cheese can reduce uric acid levels. And your doctor may recommend avoiding beer, seafood, sugar-sweetened juices and red meat (especially organ meats) because they are high in purines, a chemical that can incite a flare.  For most patients, the best way to prevent future gout attacks is to take a uric-acid-lowering medication such as allopurinol or febuxostat, Singh says.

[added Nov. 2009] The latest Science, 13 Nov, reports “Researchers have been testing the same drug against gout.” The successful new treatment is already being used for Crohns and other conditions based on errant inflammatory responses.

based on Prevention Magazine p. 83 by Andrew Weil, MDMostly I trust Weil’s opinion. One of his chief residents at his health operation connected with the Univ. of AZ for several years recently was biochem alum Dr. Yoon Kim! Some experts predict that low-carb diets could promote a surge of gout. Red meat contains purines that metabolize into uric acid, which crystallizes in joints, esp. the big toe. Dr. Weil’s recommendations of what to do:

  1. Eat bright fruits – red, blue, or purple, like cherries, berries, or dark grapes, esp. blueberries – EVERY DAY. They are rich in antioxidants and may reduce inflammationcausing gout flareups.
  2. Take fish oilsupplements – omega-3s in fish oil don’t contain the purines found in much seafood. Weil suggests starting with one 500 mg capsule, working up to as many as 4 per day.
  3. Add other omega-3foods – nuts, whole soy products, eggs, and flaxseed. The omega-3s produce prostaglandins which inhibit inflammation.
  4. Go light on meats. He mentions a study in NEJM last March, 2004 which shows lamb, beef, pork and seafood increase gout risk, while vegetables, soy, poultry, and low-fat dairy products do not.
  5. He recommends things containing turmericand ginger, bioflavonoids, flavonoids, quercetin, anthocyanins, and proantocyanins three times a day. He talks about pills for these, but dark fruits are loaded with them.
  6. He suggests lots of liquids, esp. water, to dilute the uric acid so it doesn’t crystallize. You can have wine– up to 8 ounces per day. Beer and hard liquor raise the risk of gout, but wine did not. No citation for this one.
  7. Lose weightand exerciseregularly – swimming is easiest on joints.
  8. Ibuprofen and acupuncture are helpful for pain.

Roc’s comment: Much of this makes sense, and follows many solidly proven studies supporting benefits of antioxidants (vitamin C and E), fish oil, wine, nuts, blueberries, fruit, and dairy.