SUBJ: Supplement with vitamin B3 (niacin)
SUBtitle: Competitiveness and higher status reduce aging healthspan
See past newsletters here The older you are, the less NAD+ you have in your cells. Supplementing with niacin (vitamin B3) has numerous major benefits; Early adversity and social bonds had no effect of how fast we age, but greater competitiveness and higher status caused faster aging; Alzheimers causes 60-80% of dementia cases, affects 50 million worldwide, but The Economist condemns the new Alzheimer’s drug, Aduhelm, which is very expensive and unlikely to help; An adversarial collaboration approach is being funded to decide which theory of consciousness is validated by experiments. The “Hard Problem” is how neurons provide a conscious awareness of perceptions; Bats have been used to show how “place cells” in our brains help us understand what our physical location is at any time; Eating enough antioxidants reduces Imbalance and Inflammation Markers in Atherosclerosis; Cancer patients benefit from Covid vaccine
LONG NOTES
Benefits of niacin: Science 11 Jun pg 1148: The older you are, the less NAD+ you have in your cells. Supplementing with niacin (vitamin B3) has numerous major benefits. Adipose tissue reduces reduces prediabetes effects in fat, the brain improves reducing Alzheimer’s risk, the pancreas improves insulin regulation, the vasculature reduces blood pressure, the kidneys, skeletal muscle, heart, and the immune system improve.
Aging sees many physiological changes. By measuring the accumulation of epigenetic markings on DNA, high-ranking dominant males appeared older than their chronological ages. Early adversity and social bonds had no effect, but greater competitiveness and higher status caused faster aging. Science 28 May 2021
Alzheimers causes 60-80% of dementia cases, affects 50 million worldwide. The Economist condemns the new Alzheimer’s drug, Aduhelm, which is very expensive, and 10 of 11 FDA advisors voted to reject it because it has shown no evidence of affecting Alzheimer’s. It does clear amyloid plaques from the brain, which are an indication of Alzheimer’s.
An adversarial collaboration approach is being funded to decide which theory of consciousness is validated by experiments. The “Hard Problem” is how neurons provide a conscious awareness of perceptions. Two leading theories, the global neuronal workspace theory and the integrated information theory, provide differing predictions of cause and effect of sensations to our brains. Science 28 May 201
Bats have been used to show how “place cells” in our brains help us understand what our physical location is at any time. Science 28 May 2011
METABOLIC Syndrome in an Aging Society – Role of Oxidant-Antioxidant Imbalance and Inflammation Markers in Disentangling Atherosclerosis
Cancer patients benefit from Covid vaccine. Doctors at Israel’s Beilinson Hospital monitored 102 cancer patients after inoculation with two shots of the Pfizer coronavirus vaccine. Only 10 failed to generate an antibody response.
