SUBJ: Worry is the #1 mitochondrial destroyer after smoking.
SUBtitle:. Exercise produces BAT (the good kind of fat that burns calories)
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SHORT NOTES:
1.. Worry is the #1 mitochondrial destroyer after smoking.
2..Exercise produces BAT.
3..Maria Branyas Morera was the oldest living person when she died at age 117.
4..Maria Morera evidently ate 3 yogurts daily.
5..Another centenarian: For most of her adult life, this centenarian mother was obese. She was exposed to cigarette smoke by my chain-smoking father.
6..GLP-1 Agonism Stimulates Brown Adipose Tissue.
7..Nervous system is comprised of two main types of cells: neurons and glial cells.
8..Glial cells play a wide range of regulatory and protective roles and are associated with neurons.
9..Therapeutic Potential of Acupuncture in Knee Osteoarthritis.
10..Association Between Obstructive Sleep Apnea and Reflux Disease.
11..Inflammation in Obstructive Sleep Apnea.
12..Chin Tuck Exercise contributes to Obstructive Sleep Apnea: A Case Report
LONG NOTES:
Worry is the #1 mitochondrial destroyer after smoking.
Maria Branyas Morera had been verified as the oldest living person when she died last year at age 117. At the time, Branyas was living in the small town of Olot, in the Catalonia region of Spain, where she enjoyed reading books, playing with dogs and spending time with friends and family, including her two daughters — each in their 90s. The research team learnt that Branyas’s telomeres — the stretches of repetitive DNA that protect the ends of chromosomes — were exceptionally short. Telomeres naturally shorten with age, and unusually short telomeres have been associated with age-related diseases. But Branyas had no such illnesses.
Maria Morera evidently ate 3 yogurts daily, lived 117 years and had younger mitochondria than 25 year olds. Authors of a randomized controlled trial of a
synbiotic yogurt suggest synbiotics cause the release of short-chain fatty acids, the later reduce inflammation and reducing inflammatory markers regulated mitochondria, specifically their insulin sensitivity. Their yogurt evidentlly also improved other. biomarkers of aging.
Another centenarian: For most of her adult life, this centenarian mother was obese. She was exposed to cigarette smoke by my chain-smoking father for 45 years in an 800 square foot house. In her elder years she was five feet tall and weighed over 200 pounds and had a diet that her son wouldn’t dream of eating today. He would not think any of that was key to living 100.
“GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and
Browning Through Hypothalamic AMPK”
From the Linus Pauling Institute: The nervous system is comprised of two main types of cells: neurons and glial cells (or glia). Neurons, also called nerve cells, are involved in the transmission of electrical signals and information processing. Glial cells play a wide range of regulatory and protective roles and are intimately associated with neurons. Glial subtypes include astrocytes, microglia, and oligodendrocytes. Dr. Emily Ho studies zinc and sulforaphane from cruciferous vegetables, Dr. Fred Stevens studies xanthohumol from hops, and Dr. Alysia Vrailas-Mortimer studies heavy metals and pesticides. Scientists are actively researching how brain cells respond to copper deficiency with the goal of developing therapies for Menkes disease and other childhood neurodegenerative disorders.
Therapeutic Potential of Acupuncture in Knee Osteoarthritis: Clinical Efficacy and Mechanistic Insights. These multimodal interventions position acupuncture as a dual-target treatment, mitigating symptoms while inhibiting structural degradation. However, despite promising evidence, further research is warranted for protocol standardization and long-term outcome validation. This review highlights acupuncture’s scientific legitimacy as a non-pharmacological approach for the integrated management of KOA, combining traditional methods with modern mechanistic insights.
Association Between Obstructive Sleep Apnea and Reflux Disease: A Systematic Review and Meta-Analysisx. A certain association between obstructive sleep apnea (OSA) and gastroesophageal reflux disease (RD) was observed, but this association did not reach statistical significance. RD was significantly associated with reduced sleep efficiency, but no significant relationship was found between RD and OSA severity levels.
Inflammation in Obstructive Sleep Apnea: A Global Bibliometric Perspective
Obstructive sleep apnea (OSA) is increasingly recognized as a systemic disorder in which inflammation plays a pivotal role in its pathophysiology and comorbidities.
Chin Tuck Exercise contributes to Obstructive Sleep Apnea: A Case Report
Exercise produces BAT: BAT is mainly regulated by the sympathetic nervous system (SNS); yet, recent findings have shown a group of novel activators that act independently of the stimulation of the SNS such as cardiac natriuretic peptides, irisin, interleukin-6, β-aminoisobutyric acid and fibroblast growth factor 21 that could influence BAT metabolism. Several strategies are being examined to activate and recruit BAT with no side effects. In this review, we postulate that exercise might activate and recruit human BAT through the activation of SNS, heart and skeletal muscle.
