IL-11: A cause of aging?

July, 2024 –  Omega-3 polyunsaturated fatty acids (n-3 PUFAs) can inhibit the production of interleukin 11 (IL-11) in hepatocytes (ref NIH) which is likely to extend healthspan.  [GRG] The recently published study below shows extension of lifespan with IL-11 inhibition in mice. I haven’t read the full text of the study in any detail, but glancing over it this looks like a very important finding. IL-11 inhibition appears to have not only increased maximum lifespan but the median lifespan even exceeded the maximum lifespan of wild type mice in some of the experiments, which is quite remarkable.

This IL-11 is worth watching. It provides scientific evidence and a basis for why IL-11 accelerates aging processes, and how blocking it promotes health and healing:

Scientists Discover the Holy Grail of Longevity? Blocking IL-11 To Reverse Aging & Extend Healthspan – YouTube.  Omega-3 polyunsaturated fatty acids inhibit IL-11/STAT3 signaling.  So getting plenty of fish and other omega-3s extends healthspan.