More reasons and ways to take aspirin

Baby Aspirin every day: Study published in 2001 of 4,500 people at high risk for heart disease (100mg per day) reduced the risk by 44%. See Article 4 below.

ARTICLE 1: N Engl J Med. 1997 Apr 3;336(14):973-9. “Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men”, Paul M. Ridker, M.D., Mary Cushman, M.D., Meir J. Stampfer, M.D., Russell P. Tracy, Ph.D., and Charles H. Hennekens, M.D.

ARTICLE 2: 2015 Getting a dose of 100mg or less daily reduces stroke risk. Aspirin for the Primary Prevention of Cardiovascular Events: A Systematic Evidence Review for the U.S. Preventive Services Task Force [Internet].

ARTICLE 3: 325 mg of aspirin on alternate days -Clin Appl Thromb Hemost. 2001 Jan;7(1):53-7. A comparison of every-third-day versus daily low-dose aspirin therapy on serum thromboxane concentrations in healthy men and women. Feldman M1, Cryer B, Rushin K, Betancourt J. treatment with 325 mg of aspirin every third day or 81 mg of aspirin per day (86% inhibition [84%, 89%] and 85% inhibition [73%, 96%], respectively

Recent studies indicate that…long-term use of aspirin may reduce the risk of Alzheimer’s by reducing inflammation of the brain. Not only did daily use protect against dementia, but also that risk continued to drop as the duration of NSAID use increased. Results were the same in women and in men. Harvard Women’s Health Watch, April, 1998

The longest primary prevention trail of cancer and one of the largest, 22,071 male physicians, 12 year trial. “The randomized aspirin component ended early, after five years, primarily because of a statistically extreme benefit of aspirin on risk of a first heart attack.” 325 mg aspirin every other day were taken. Hornbach-Torres, T., “Physicians’ Health Study Shows Beta Carotene Supplements to be Without Benefit or Harm”, Press Release, Report on Women’s Health Study, Jan. 19, 1996, [617-732-5008]-

“…results show a significant reduction in the incidence of ischemic events in patients in the [400 IU] vitamin E plus aspirin group compared with patients taking only aspirin”. This study also shows the natural ratio of two important closely related antioxidants. a-tocopherol is vitamin E. g-tocopherol is a closely related molecule also critical to preventing LDL oxidation. They naturally occur in a ratio of 5:1. According to a private conversation with Dr. Bruce Ames, a world-famous expert at UC-Berkeley, one problem with commercial vitamin E is that it usually contains only a-tocopherol, and that when taken, this displaces the g-tocopherol in LDL. Thus, a formulation containing 5:1 a- to g-tocopherol is preferable to one containing only a-tocopherol.” Steiner, M. , Glantz, M. , and Lekos, A., “Vitamin E Plus Aspirin Compared With Aspirin Alone In Patients With Transient Ischemic Attacks”, Am. J. Clin. Nutr. 62(suppl): 1381S-4S (1995)