SUBJ: Eat salmon for health
SUBtitle: Hand grip strength a vital sign of health
From Kevin: “The biggest poison that we face around the world internally in our societies and externally in our relations with others is dehumanization – the inability to see the humanity in the other.”
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SHORT NOTES:
Scientists find compounds in salmon that may lower cholesterol, heart disease risk.
FDA Clears First Non-drug Prescription Device for Women with Osteopenia
7 Worst Habits for Your Joints: 2. Lack of exercise 3. Too much exercise. 4. Carrying loads requiring two hands to carry 5. red meat…. 6. constant typing on cellphone 7. Skimping on sleep.
Walking for pleasure is negatively correlated with knee osteoarthritis (KOA).
Exercise delays death and prevents cognitive and physical decline.
The Association Between the Composite Dietary Antioxidant Index and reduced Frailty.
Only very weak correlations between red meat consumption and various diseases. ROC comments: This is just one paper.
Myth #1: E-cigs are a safer alternative to smoking cigarettes
Myth #3: You can use e-cigs indoors.
“The United States spends significantly more on healthcare compared to other nations but does not have better healthcare outcomes.”
SAβ-gal still remains the most commonly used marker to detect senescent cells.
NAD+ supplementation prevents STING-induced senescence in CD8+ T cells.
An accurate aging clock was developed from large-scale gut microbiome and human gene expression data.
LONG NOTES:
Scientists find compounds in salmon that may lower cholesterol, heart disease risk. The study found that salmon contains 508 food-specific compounds, or FSCs, including 237 metabolites that are unique to salmon.
Hand grip strength as a proposed new vital sign of health: a narrative review of evidences Hand grip strength (HGS) is a crucial measure of muscle function, particularly in the aging population. This review highlights its relevance to health, showing that HGS can reliably assess muscle strength. Low HGS is associated with various diseases and health issues, making it a valuable biomarker and potential vital sign throughout life.
FDA Clears First Non-drug Prescription Device for Women with Osteopenia
AARP The 7 Worst Habits for Your Joints: 1. Smoking 2. Lack of exercise 3. Too much exercise. 4. Carrying loads requiring two hands to carry 5. red meat, white sugar, French fries, soda, pastries. 6. constant typing on that mini keyboard (aka, your cellphone) “creates inflammation of the joints and tendon sheaths, 7. Skimping on sleep
Does Walking Have an Association with Osteoarthritis? From genetic studies, types of physical activity in last 4 weeks: Walking for pleasure (not as a means of transport) is negatively correlated with knee osteoarthritis (KOA), but there is no clear evidence supporting its correlation with hip osteoarthritis
A quick and easy guide on exercise for longevity . Exercise delays death and prevents cognitive and physical decline.
The Association Between the Composite Dietary Antioxidant Index and Frailty Symptoms: Mediating Effects of Oxidative Stress. The aim of this study was to examine the relationships between the composite dietary antioxidant index (CDAI) and frailty and the underlying mechanisms involved. Frailty is negatively associated with the CDAI score, which may be partially mediated by oxidative stress.
From a reader: Not sure if you have seen this before: large analysis finds only very weak correlations between red meat consumption and various diseases. Red meat is not a health risk. New study slams shoddy research – One of the primary reasons for unreliable past research is the inclusion of all types of red meat including processed meat, meat cooked with high temperatures, etc…ROC comments: This is one paper. Red meat contains a substantial amount of saturated fat, which contributes directly to various diseases, and is a substantial cause of global warming. I love a little red meat occasionally, but wish I was a vegetarian.
Myth #1: E-cigs are a safer alternative to smoking cigarettes
Myth #3: You can use e-cigs indoors.
“The United States spends significantly more on healthcare compared to other nations but does not have better healthcare outcomes.”
In 1995, Prof. Campisi discovered a senescence marker – named senescence-associated beta galactosidase or SAβ-gal – that enabled scientists to detect senescent cells both in cell culture and in vivo. Almost 30 years and 8000 citations later, SAβ-gal still remains the most commonly used marker to detect senescent cells. Some notable examples of its use include the seminal papers showing that removal of senescent cells can extend lifespan in mice and the discovery that senescent cells play a role in growth and patterning during mammalian embryonic development.
NAD+ supplementation prevents STING-induced senescence in CD8+ T cells by improving mitochondrial homeostasis. The study finds that mitochondrial dysfunction leads to T-cell aging and senescence, mediated by the cGAS-STING pathway. Increasing NAD+ levels with nicotinamide mononucleotide (NMN) can prevent this senescence and improve immune function and survival in mice.
An accurate aging clock developed from large-scale gut microbiome and human gene expression data. Utilizing a large dataset of 90,303 stool samples, the study developed a refined microbiome-aging model, revealing correlations between biological age and lifestyle or health factors—such as higher predicted ages in individuals on a paleo diet or with IBS, and lower in vegetarians.
