SUBJ: Taurine deficiency as a driver of aging
SUBtitle: sucralose-sweetened drink exceeds” the threshold of toxicology in Europe
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SHORT NOTES: Taurine deficiency as a driver of aging; daily sucralose-sweetened drink [in the U.S.] exceed” the threshold of toxicology by the European Food Safety Authority; Vitamin D status does not affect muscle strength in older adults; elevated levels of plasma EPA erythrocyte membrane DHA were associated with a lower risk of cognitive decline; increasing dietary cruciferous vegetables intake could be a promising strategy to attenuate recurrence and progression risks in patients with bladder cancer; Higher intake of flavan-3-ol after colon cancer diagnosis was associated with lower colorectal cancer-specific mortality; polyunsaturated fatty acids and elemental metals do not appear to effectively reduce perinatal depression; A double-blind, parallel randomized controlled trial was conducted in 61 healthy older individuals aged 65–80 y with blueberries giving significant increase in flow-mediated dilation and reduction in arterial stiffness, and systolic blood pressure; Prenatal vitamin D deficiency is associated with asthma or recurrent wheezing in offspring; Fecal microbiota transplantation holds the secret to youth; “A daily multivitamin may help slow memory loss in people age 60 and older”; A man spent 93 days at the bottom of the Atlantic – now he’s 10 years younger; This video by the owner/director of the Gerontology Research Group (of which I am a member) presents his vision for the effort to extend human life span; Alpha TAU’s last clinical trial of Alpha DaRT on recurring skin cancer trials and for pancreatic cancer; for Autism, inhibiting production of NO increased “social” behavior, and interest in new objects while reducing repetitiveness and anxiety; an injector to implant multiple strands of hair to the scalp, under local anesthetic, to instantly restore hair to women struggling with baldness; The Federal Reserved recently released a report that outlines the devastating impact of health care costs on patient care access; a push to more carefully consider the potential adverse effects of 3 hours per day of social media on young people fostering depression, anxiety and other mental health problems; metabolic rate can be inversely related to aging so fasting is useful; populations exposed to famine revealed that exposure to food deprivation is associated to lasting health-related effects for the exposed individuals; things your body needs as you age-calcium (this is incorrect, previous newsletter explained hazard of calcium supplements-to avoid osteoporosis, just get vitamin D and weight bearing exercise), vitamin B6(supplement), B9(salad), B12 (meat), D, magnesium from nuts, seeds, and leafy greens, probiotics from yogurt, cole slaw or sauerkraut, fish or fish oil, zinc, selenium from a Brazil nut daily, potassium (banana), fiber.
LONG NOTES:
Remarkable Rejuvenation Effects of Taurine. an article about taurine claiming 1.5 grams/day evidently increased levels of the antioxidant enzyme superoxide dismutase (SOD) in women aged between 55 and 70.
https://www.lifeextension.com/magazine/2023/7/longevity-effects-of-taurine
“Taurine may be a key to longer and healthier life”
https://medicalxpress.com/news/2023-06-taurine-key-longer-healthier-life.html
https://invidious.snopyta.org/watch?v=mv1t4QNp_X8
Taurine deficiency as a driver of aging
https://www.science.org/doi/full/10.1126/science.abn9257
The trace amounts of sucralose-6-acetate in a single, daily sucralose-sweetened drink [in the U.S.] exceed” the threshold of toxicology that is part of the restrictions imposed by the European Food Safety Authority.
AJCN June – Vitamin D status does not affect muscle strength in older adults; Previous data have linked omega-3 fatty acids with risk of dementia. Moderate-to-high levels of evidence indicated that elevated levels of plasma EPA erythrocyte membrane DHA were associated with a lower risk of cognitive decline. Dietary intake or long-term supplementation of omega-3 fatty acids may help reduce risk of AD or cognitive decline; High recurrence and progression rates are major clinical challenges for non–muscle-invasive bladder cancer(NMIBC). Given the compelling preclinical evidence, increasing dietary dietary isothiocyanates exposure with cruciferous vegetables intake could be a promising strategy to attenuate recurrence and progression risks in patients with NMIBC; Higher intake of flavan-3-ol after CRC diagnosis was associated with lower colorectal cancer-specific mortality; Despite their widespread popularity, polyunsaturated fatty acids and elemental metals do not appear to effectively reduce perinatal depression. Vitamin D taken in doses of 1800–3500 International Units per day may be, to some extent, promising; A double-blind, parallel randomized controlled trial was conducted in 61 healthy older individuals aged 65–80 y. A significant increase in flow-mediated dilation and reduction in 24 h cognitive function, arterial stiffness, ambulatory systolic blood pressure were found in the 26 g of freeze-dried wild blueberry group compared with the placebo group; Prenatal vitamin D deficiency is associated with asthma or recurrent wheezing in offspring. Pregnant women with severe vitamin D deficiency show the greatest 25(OH)D improvement because of supplementation. In these women, a vitamin D dose of 4400 IU might have a preventive role in the development of early life offspring asthma or recurrent wheezing. Gestational age is suggested to modify the efficacy of prenatal vitamin D supplementation, showing the highest beneficial effect if supplementation is started during the first trimester of pregnancy.
Fecal microbiota transplantation holds the secret to youth
• The microbes that live in a person’s digestive tract significantly impact their overall health and age. It aids in metabolism and nutrition intake, keeps the immune system strong, and helps the body process food more efficiently.
- There is much evidence linking shifts in intestinal bacteria with the aging process in humans. Diseases like insulin intolerance, diabetes, heart disease, Alzheimer’s, and even depression have been linked to alterations in the intestinal flora.
- Intestinal bacteria benefit from both variety and consistency. Older people may be at increased risk of dying prematurely due to a lack of variety in their gut bacteria. The most straightforward way to alter the makeup of gut microbiota is through fecal microbiota transplantation, which involves the introduction of beneficial microorganisms into the human intestine in the hopes that they will restore microbial equilibrium by balancing out the preexisting fungus, viruses, and bacteria. This demonstrates FMT’s significant impact on well-being, life, and age.
new study in the American Journal of Clinical Nutrition reports that: “A daily multivitamin may help slow memory loss in people age 60 and older”
GRG: A man spent 93 days at the bottom of the Atlantic – now he’s 10 years younger. This is fascinating if true. I’d never heard of high atmospheric pressure alone as a longevity intervention. Apparently, his telomeres grew by 20% and he has 10x more stem cells in addition to cutting his inflammatory markers in half.
This video by the owner/director of the Gerontology Research Group (of which I am a member) presents his vision for the effort to extend human life span. 12 minutes long, but does show ideas for extending our lives.
Following the 100% success of Israel’s Alpha TAU’s last clinical trial of Alpha DaRT on recurring skin cancer (see here previously) medical institutes around the world are clamoring to participate in the upcoming pivotal trials. Alpha TAU has also begun clinical trials for pancreatic cancer.
Autism indicators increase as Nitric Oxide increases in the brain. Conversely, inhibiting production of NO increased “social” behavior, and interest in new objects while reducing repetitiveness and anxiety.
Israel’s Hairstetics has developed an injector to implant multiple strands of hair to the scalp, under local anesthetic, to instantly restore hair to women struggling with baldness. Women suffering from androgenic alopecia receive non-allergenic synthetic hair to match their own hair color.
The Federal Reserved recently released a report that outlines the devastating impact of health care costs on patient care access. The report notes that “in 2022, 28% of adults went without some kind of medical care because of the high cost.” Furthermore, 23% of USA adults in 2022 had a major, unexpected medical expenditure with the “the median amount for those major bills…between $1,000 and $1,999.
In an unprecedented report, USA Surgeon General Vivek Murthy, MD issued a 19-page public health advisory calling attention to the potential risks of social media on young people. The report urged for a push to more carefully consider the potential adverse effects of social media by fostering depression, anxiety and other mental health problems
The June 5 Fight Aging! newsletter includes a discussion about how metabolic rate can be inversely related to aging. When Ithis GRG member fasts for 72 hours or so he invariably senses his body is “going into hibernation.” Fasting can lead to a sensation of lower metabolic rate, and that sense is something to strive for while fasting.
Historical and demographical human cohorts of populations exposed to famine, as well as animal studies, revealed that exposure to food deprivation is associated to lasting health-related effects for the exposed individuals, as well as transgenerational effects in their offspring that affect their diseases’ risk and overall longevity.
WebMD – things your body needs as you age-calcium (this is incorrect, previous newsletter explained hazard of calcium supplements-to avoid osteoporosis, just get vitamin D and weight bearing exercise), vitamin B6(supplement), B9(salad), B12 (meat), D, magnesium from nuts, seeds, and leafy greens, probiotics from yogurt, cole slaw or sauerkraut, fish or fish oil, zinc, selenium from a Brazil nut daily, potassium (banana), fiber.
