SUBJ: Pro-, prebiotic supplements reduce all-cause and cardiovascular mortality
SUBtitle: impact of sleep on obesity and body composition
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SHORT NOTES: We found a protective effect of Pro-, pre-, and synbiotic supplements for all-cause and cardiovascular mortality in Americans aged 65 years or older [synbiotics contain pre- and pro- together.]; The impact of sleep on obesity and body composition is well-known, and many studies have shown an association between insufficient or excessive sleep duration and obesity, body fat percentage, and weight gain; Alpha-ketoglutarate as a potent regulator for lifespan and healthspan; I will keep you posted on this skin rejuvenation cream-Topical rapamycin for slowing skin aging; ARPA-H takes on arthritis; Brain-spine computer link helps paralyzed man walk; new coronavirus vaccine will be released this; new advances in regenerative medicine overcome roadblocks to rejuvenating our bodies; Insights into the Role of Inflammation in the Management of Atherosclerosis; Free Webinar From WebMD, June 8, 2pm ET, Topic: When You Have Obesity and Diabetes Register
LONG NOTES:
We found a protective effect of Pro-, pre-, and synbiotic supplements for all-cause and cardiovascular mortality in Americans aged 65 years or older. A total of 1556 participants died during the median 77 months follow-up, and 517 died from cardiovascular disease. Compared with participants without nonfood pro-, pre-, and synbiotics use, nonfood pro-, pre-, and synbiotics use reduces nearly 41% risk of all-cause mortality (hazard ratio 0.59, 95%CI 0.43 to 0.79) and 52% risk of cardiovascular mortality. Nonfood pro-, pre-, and synbiotics can be a novel, inexpensive, low-risk treatment addition for all-cause and cardiovascular mortality for older individuals.
The impact of sleep on obesity and body composition is well-known, and many studies have shown an association between insufficient or excessive sleep duration and obesity, body fat percentage, and weight gain. However, there is growing evidence of the effects of body composition on sleep and sleep disorders (particularly sleep disordered breathing) through anatomical and physiological mechanisms (nocturnal fluid shift, core body temperature, or diet). Although some research has been conducted on the bidirectional effects of sleep-disordered breathing and body composition, the specific effects of obesity and body composition on sleep and the underlying mechanisms that explain these effects remain unclear. Therefore, this review summarizes the findings on the effects of body composition on sleep and draws conclusions and proposals for future research in this field.
Alpha-ketoglutarate as a potent regulator for lifespan and healthspan: Evidences and perspectives. Alpha-Ketoglutarate controls stem pluripotency and self-renewal. Alpha-Ketoglutarate supports fertility in animal models. Alpha-Ketoglutarate is a key metabolite in regulating cancer cell behaviors.
[Some people are trying this skin rejuvenation method. I will keep you posted on the progress. Hope for those of us with saggy skin, wrinkles, etc.] Skin Rejuvenation as reported by Turn.bio. Topical rapamycin for slowing skin aging. 1) Someone felt like a mad scientist putting everything together but pulled together a lot of info from this site and others and produced my own topical cream this morning.Science 26 May pg 776-ARPA-H takes on arthritis, Advanced research projects Agency has its first program to aid 32 million people in the US with arthritis; pg 777-Brain-spine computer link helps paralyzed man walk, navigate obstacles with his own legs; pg 779-new coronavirus vaccine will be released this fall with greater levels of protection from virus variations; pg 797-new advances in regenerative medicine overcome roadblocks to rejuvenating our bodies.
Insights into the Role of Inflammation in the Management of Atherosclerosis
After decades of studies, the understanding of atherosclerosis has evolved dramatically, and inflammation has been recognized as one of the most relevant pillars in all phases of atherosclerotic disease. Nevertheless, only recently, the trial CANTOS, and subsequent outcome studies with colchicine, finally provided proof-of-concept evidence that anti-inflammatory therapies were able to reduce cardiovascular events with no influence on lipid levels.
Free Webinar From WebMD, June 8, 2pm ET, Topic: When You Have Obesity and Diabetes Register
