SUBJ: tips for healthy aging
SUBtitle: natural maximum human life span is 120 to 125 years
Welcome to many new subscribers. I try to send this every Saturday morning, as just reading about nutrition like this once a week will increase your healthspan 7 years. I notice WebMD and AARP are bombarding us with long slide shows wasting too much time.
Join a study this summer for my readers. I hope you heard the ESPN Program on this website, to be available in a link soon. And my presentation to a cancer biomedical symposium will be available by the end of this month. For new readers: how to get newsletter, links to nutritionconsensus.org/products; whyweage; 46steps to slow aging; Key word search command
SHORT NOTES: 23 GRG tips for healthy aging e.g.Cold Water Immersion, High-Intensity Interval Training (HIIT, Intermittent Fasting;. ‘Disruptive’ science has declined – and no one knows why; Scientists have developed therapy for multiple myeloma and amyloidosis; 2,500+ US physicians have prescribed the Nerivio migraine relief device; New way to cure pulmonary embolisms, No blood thinners, no invasive surgery; US approval for pineapple plant-based burns treatment; Can ageing be cured? Children born today in prosperous countries are very likely to live into their 90s. Scientists say the natural maximum human life span is 120 to 125 years; The Stage is Set for Rapid Progress Towards Human Longevity in the Next Decade, The newest scheme is to hack the ageing process itself by reprogramming old cells to a younger state; people who used glucosamine had a lower risk of dying from cancer than those who did not; a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity Klotho.
LONG NOTES:
GRG tips – 1. Cold Water Immersion 2. High-Intensity Interval Training (HIIT) 3. Intermittent Fasting 5. Meditation 6. Lift those barbells 7. Block Blue Light 8. Creatine for cognition 9. Air purifier 10. Sweating it out in the sauna 11. Oil pulling for oral health Proponents of oil pulling claim that it can have a number of health benefits, including improving oral health, reducing inflammation, and boosting the immune system. 13. Omega 3 foods 15. Rise and shine with proteins and fats 16. Add some zing to your workouts 18. Stand up 21. Gut feeling The gut is home to 70% of our immune system. Probiotics include Pickles, Sauerkraut, Kimchi, Kefir, and Yogurt. Prebiotics include Asparagus, Onions, Leeks, Garlic, Apples, and Bananas. 22. Mouth taping Mouth taping avoids breathing from the mouth which for a prolonged time causes obstructive sleep apnea. 23. Magnesium Supplementation Consuming a tablet of Magnesium Glycinate or Magnesium Threonate before sleep supports muscle, and nerve function and energy production.
‘Disruptive’ science has declined – and no one knows why As in any organization, graduate students, who drive most scientific research, cannot change the whole system alone. For a significant change, we need support from department leadership, PIs, and the entire university culture.
Scientists have developed HBI0101- a CAR-T therapy for multiple myeloma and amyloidosis, benefiting over 90% of patients in trials. Los Angeles-based Immix BioPharma will commercialize HBI0101.
Relieving migraines in the US. 2,500+ US physicians have prescribed the Nerivio migraine relief device from Israel’s Theranica, benefiting some 35,000 Americans with its neuromodulation technology.
New way to cure pulmonary embolisms. Doctors at Jerusalem’s Hadassah hospital removed a blood clot in an Israeli’s lung (pulmonary embolism) using, for the first time in Israel, a US-developed FlowTriever. It sucked out some of the patient’s blood, cleaned it of the clot and replaced it. No blood thinners, no invasive surgery.
US approval for burns treatment. Israel’s Mediwound has received FDA approval for its NexoBrid pineapple plant-based burn treatment (see here previously) to be sold in the US to treat thermal burns. The US already has emergency stockpiles.
GRG: Can ageing be cured? Children born today in prosperous countries are very likely to live into their 90s. Scientists are giving it a try. Cutting-edge technologies are revealing the intricacies of human ageing and sparking research into drugs to slow it, or even reverse it. “If you’re a mouse, you’re a lucky creature because there are a lot of ways to extend your life span, And long-lived mice seem very happy.” Between 1900 and 2020, human life expectancy more than doubled, to 73.4 years. But that remarkable gain has come at a cost: a staggering rise in chronic and degenerative illnesses. And more might reach what is believed to be the natural maximum human life span, 120 to 125 years. Over the past few years, investment in the industry has come from tech tycoons, overnight crypto millionaires, and most recently Saudi royals. It seems everyone with cash to burn is placing a bet on ageing’s next—or really, its first—big thing.
The Stage is Set for More Rapid Progress Towards Human Longevity in the Next Decade. The state of the field has changed greatly over the last decade, not least of these changes being a vast increase in the funding devoted to clinical translation of age-slowing and rejuvenation therapies. Cynically, I suspect that it is the funding that ensures that the popular science press takes a more respectful tone than they did ten years ago. It is much harder to advance (in writing!) a knee-jerk dismissal of a field of science when billions of dollars of funding and many large, conservative institutions are involved, as they are these days. Rapamycin, widely prescribed to prevent organ rejection after a transplant, increases the life expectancy of middle-age mice by as much as 60 percent. Drugs called senolytics help geriatric mice stay sprightly long after their peers have died. The diabetes drugs metformin and acarbose, extreme calorie restriction, and, by one biotech investor’s count, about 90 other interventions keep mice skittering around lab cages well past their usual expiration date. The newest scheme is to hack the ageing process itself by reprogramming old cells to a younger state. In industrialised nations, about one in 6,000 reaches the century mark and one in five million makes it past 110. This work is powered by artificial intelligence, big data, cellular reprogramming, and an increasingly exquisite understanding of the zillions of molecules that keep our bodies humming.
November 2, 2022 in the journal Frontiers of nutrition men and women who used glucosamine had a lower risk of dying from cancer than those who did not use glucosamine.
Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity. Klotho for arthritis – This is a compound that still requires genetic engineering, but shows promise for reversing or preventing arthritis one day.
