SUBJ: Roc is thankful for knowledge to maintain health
There is an avalanche of articles about nutrition and health. Here are key choices:
SHORT NOTES: Social engagement was the most important factor in preventing mild cognitive impairment; Do you have dementia or just Early memory loss; Reduce inflammation by getting enough vitamins A and E; Five new prize winning medical treatments doctors ought to know for sleep apnea, stroke, diabetes, afib, and heart failure; Religious traditions have guidance for health; Short sleep duration and insomnia contribute to stroke risk; Parents of children with poor sleeping habits are at risk; Knee cartilage implant Agili-C reduces arthritis pain; Taking a combination of 1g leucine and 50mg resveratrol supplements has numerous healthspan benefits; nightly doses of melatonin, strontium (citrate), vitamin D3 and vitamin K2 increased bone mineral density in postmenopausal osteopenic women in lumbar spine and left femoral neck; Israeli scientists reverse aging process with hyperbaric oxygen therapy increasing telomere length and reducing senescent cells; Competition to support longevity activism, advocacy and raising public awareness gave an honorable mention to Roc Ordman – Nutrition Investigator; Remember discount code ROC when ordering Triumph. Then cost is $34.95
I am thankful better days are coming. -Roc
LONG NOTES
Mild Cognitive Impairment was closely related to lifestyle; social engagement was the most important factor in predicting the occurrence of MCI
https://www.dovepress.com/article_58594.t126227935
Early memory loss or dementia: https://www.aarp.org/health/brain-health/info-2015/normal-memory-loss-vs-dementia-quizl?cmp=EMC-DSO-NLC-WBLTR-BRN–MCTRL-112020-F1-5018787&ET_CID=5018787&ET_RID=47940218&encparam=JhPrVLqyiN0H6%2fFQ%2fi%2bHwuYUNgy2g2YITgAk8Ur88w4%3d#quest1
NEGATIVE Correlation Between Vitamin A and Positive Correlation Between Vitamin E and Inflammation Among Healthy Adults in Korea: Based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2016–2018 7th Edition
Authors: Hong KH, Lee Y
https://www.dovepress.com/article_58698.t126153466
Five new prize winning medical treatments doctors ought to know:
1. Product recommended for sleep apnea https://vimeo.com/471151677/d8e6079f18
2. Great new technology your hospital should have for immediate treatment of stroke: https://vimeo.com/471129658/794db555b0
3. Treatment developed at Mayo Clinic to prevent progression of type 2 diabetes: https://vimeo.com/471445655/edc7cc2ede
4. Treatment for cardiac arrhythmias: https://vimeo.com/471030419/700611261a
5. Preventing fluid overload after heart failure, major issue after heart attack: https://vimeo.com/471152583/11f5b701be
Reader comment: I am intrigued by the report of benefits from fasting during Ramadan. I’ve often, at science-and-religion conferences, complained that scientists too rarely look at the old texts or practices as sources of experiments. E.g the Torah strongly condemns living in a house with mold, and both Jews and Muslims have known for centuries that if the cow is too sick to walk, you cannot eat it.
We provided suggestive evidence for a potential causal role of short sleep duration and insomnia symptoms in risk of large artery stroke.
https://www.dovepress.com/article_58373.t126160075
Parents of children with sleep disturbances experience poor sleep and high pre-sleep arousal, indicative of insomnia.
https://www.dovepress.com/article_58744.t126160075
Knee cartilage implant is a breakthrough. (TY Atid-EDI) Israel’s CartiHeal (reported here previously) has received US FDA breakthrough device designation for its Agili-C implant. Agili-C has been implanted in over 500 study patients with knee, ankle and big toe cartilage lesions in trials at leading centers in Europe and Israel.
https://www.prnewswire.com/il/news-releases/cartiheal-receives-fda-breakthrough-device-designation-for-the-novel-agili-c-implant-301150023l
Modulation of Energy Sensing by 1g Leucine Synergy with Natural Sirtuin
Activators: Effects on Health Span
Michael B. Zemel
Published Online:6 Nov 2020https://doi.org/10.1089/jmf.2020.0105
Abstract
Sirt1 and 5′ adenosine monophosphate-activated protein kinase (AMPK) are
energy-sensing systems that work cooperatively and regulate
mitochondrial biogenesis and fuel metabolism, and mediate, in part, the
salutary effects of caloric restriction on lifespan and healthspan. We
have shown that leucine activates Sirt1 and enables synergy with sirtuin
co-activators. Resveratrol is a widely recognized activator of Sirt1;
however, poor bioavailability and rapid metabolism limit effective
clinical translation of promising animal data. However, we found that
combining low resveratrol doses with leucine increased skeletal muscle
and adipocyte Sirt1 activity, mitochondrial biogenesis and fatty acid
oxidation; these effects result in increased lifespan and marked
reductions in insulin resistance, inflammatory markers, body weight, and
visceral adiposity in preclinical models.
FALLS Risk, Circadian Rhythms and Melatonin: Current Perspectives
Authors: Goswami N, Abulafia C, Vigo D, Moser M, Cornelissen G, Cardinali D
https://www.dovepress.com/article_59173.t126978550
The development of geroprotectors is an active field of research.
External synchronizers are important to keep circadian rhythms in sync. A chronobiologic approach can thus save lives. It can also save costs, as suggested by a few case studies. Compared to placebo, one-year treatment with melatonin did not affect postural balance or risk of falls nor modified muscle strength. A number of studies point out to a preventive role of melatonin in sarcopenia.60,61 In humans, bone mineral density in the femoral neck of postmenopausal osteopenic women increased in response to melatonin in a dose‐dependent manner when compared with a placebo.68 Likewise, in a one-year double blind randomized control trial assessing the effects of nightly melatonin, strontium (citrate), vitamin D3 and vitamin K2 on bone mineral density in postmenopausal osteopenic women treatment increased it in lumbar spine and left femoral neck.69 The circadian amplitude of melatonin decreases as a function of age, raising the questions whether such a decrease in the circadian amplitude of melatonin relates to a higher risk of falls and, if so, whether melatonin supplementation may be an effective countermeasure.
Israeli scientists reverse aging process. In the first trial on humans, Israeli scientists have shown hyperbaric oxygen therapy (HBOT) can reduce two key biological hallmarks of aging – telomere length shortening and accumulation of senescent cells. These factors lower the risk of cancer, dementia, Alzheimer’s and much more.
https://www.prnewswire.com/il/news-releases/first-time-human-study-shows-reversal-in-biology-of-aging–telomere-shortening-and-senescent-cells-accumulation–with-hyperbaric-oxygen-therapy-hbot-301176053l
https://www.aging-us.com/article/103571
The International Longevity Alliance announces the winners of the first of its kind prize Competition to support longevity activism, advocacy and raising public awareness about longevity research. In addition, recognition and commendation are given to the other participants: Roc Ordman – Nutrition Investigator, USA
Remember discount code ROC when ordering Triumph. Then cost is $34.95
