SUBJ: Exercise slows cognitive decline.
SUBtitle: Midlife Weight Loss May Trigger Brain Inflammation
Well done is better than well said! Poor Richard’s |Almanac
Links for new readers: 1) Instructions for new subscribers to use this newsletter and website 2) One Day in Roc’s Life: 46 resolutions to prolong health span
I am thankful to all who read my newsletter, and grateful to those who sponsor it. Link to subscribe to newsletter
To be removed from the nutrition list distribution, please email ordman@beloit.edu SUBJ: remove from list. All writings are to discuss with your physician. Full Disclaimer
SHORT NOTES:
1.. Exercise slows cognitive decline.
2.. Midlife Weight Loss May Trigger Unexpected Brain Inflammation.
3.. cancer incidence is a function of lifespan and physiological, not chronological, aging.
4.. Functional Exercise Program for Elderly Patients After Total Knee Arthroplasty.
5.. Heat-activated, iron-oxide nanoparticles that use heat to destroy cancer cells.
6.. November focuses on prostate cancer, testicular cancer, suicide prevention and men’s mental health.
7..Learning doesn’t have to slow down with age.
8..A Novel Butyrate Generator Helps Modulate the Gut-Brain Axis.
LONG NOTES:
Science 4 Dec pg 1014 – Exercise slows cognitive decline. Best is 5,000 to 7,500 steps per day in the sedentary group. Pg 1013-Cockroach allergens cause asthma and other allergies in children. Exterminators remove the pests and the hazard.
Why I don’t want to go on a diet. Midlife Weight Loss May Trigger Unexpected Brain Inflammation. Scientists at Israel’s Ben-Gurion University have discovered that when obese middle-aged mice lose weight, it aggravates inflammation in the hypothalamus, a brain region that governs appetite, energy balance, and numerous essential functions. And I don’t want to stop eating cheese.
The evolution of lifespan and age-dependent cancer risk. A theoretical review of the current paradigm and discuss some fundamental evolutionary theory postulates that explain why cancer incidence is a function of lifespan and physiological, not chronological, aging. carcinogenesis typically requires 6–7 mutations and/or other cell alteration to malignantly transform a cell, based on the evidence that the age-dependent exponential increase in cancer incidence follows mathematically the 6th power of age. It is becoming clear that carcinogenesis is a more complicated process regulated by many forces beyond the occurrence of oncogenic mutations.
Applying the Knowledge-to-Action Framework to Implement and Evaluate an Evidence-Based Functional Exercise Program for Elderly Patients After Total Knee Arthroplasty: A Mixed-Methods Study. T he evidence-based rehabilitation program significantly enhanced functional recovery parameters, and pain control efficacy compared to standard care. Guided by the Knowledge-to-Action (KTA) Framework, this study comprised two sequential phases. In the knowledge creation phase, we systematically synthesized evidence through comprehensive retrieval, critical appraisal, and integration of high-quality rehabilitation programs for elderly patients undergoing TKA from domestic and international literature. During the action cycle phase, expert panel discussions and stakeholder interviews were conducted to identify barriers and facilitators of implementation, culminating in the co-development of a finalized intervention program
Turning up the heat on cancer. (TY UWI & I24 News) Israeli startup New Phase (see here previously) is conducting a clinical trial on 27 patients of its heat-activated, iron-oxide nanoparticles that use heat to destroy cancer cells from the inside. It provides a low-toxicity method of slowing down metastasis and extending life.
Movember for men’s health. Throughout November, Israeli men were urged to get regular check-ups and screenings, and to lead healthier lifestyles. The Movember campaign began in Australia (Mo is Australian slang for moustache) and focuses on prostate cancer, testicular cancer, suicide prevention and men’s mental health.
Learning doesn’t have to slow down with age. (TY TPS) Researchers at the Hebrew University of Jerusalem and at the Stanford Center for Longevity has proved that older adults learn best when education taps into their motivations, connects new knowledge to previous experience, and allows for active engagement. In conclusion, our conceptual analysis shows that although older learners have unique characteristics, all five core features of the LS model fit them at least as well as they fit younger learners.
A Novel Butyrate Generator Helps Modulate the Gut-Brain Axis: A Randomized Double-Blind Placebo-Controlled Clinical Study. These results suggest that ButyraGen may supports both psychological and physiological well-being, particularly in men, younger individuals, and those without gastrointestinal disease. Benefits began to appear within weeks two and three and were sustained through six weeks, highlighting its potential as a fast-acting intervention for both gut and brain health, indicative of the gut-brain axis connection.
