SUBJ: Music heals chronic pain.

SUBtitle: personal practices to thrive as an elder

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SHORT NOTES:

Music heals chronic pain.

Nobel laureate personal practices to thrive as an elder depend on healthy eating, prioritizing sleep, and performing stimulating mental and physical activities.

Diseased heart releases bubbles that travel through the bloodstream and promote the growth of cancer cells.

David Sinclair, Harvard professor, Hopes Rejuvenation Possible in a Few Decades.

Plasma donation induces a beneficial protein expression profile shift in circulating human blood.

LONG NOTES:

Science 22 March pg 1271: Music heals chronic pain.  Those who sang solo experienced some pain relief, whereas the group singers were dramatically benefited y every measure of chronic pain. Their measure of generosity was also substantially increased. Pg 1300-Why do we die? By Nobel laureate Ramakrishnan. He is sober about the complexity of aging biology.  His personal practices to thrive as an elder depend on healthy eating, prioritizing sleep, and performing stimulating mental and physical activities.

Researchers at Tel Aviv University and Sheba Medical Center found that a diseased heart releases bubbles, called extracellular vesicles (sEVs). These travel through the bloodstream and promote the growth of cancer cells. Spironolactone stops sEVs and prevents cancer.

In this new interview, David Sinclair, Harvard professor and the author of “Lifespan”, explains his theory of aging, shares parts of his health routine, and reveals which directions in today’s aging research excite him. David Sinclair Hopes Rejuvenation Possible in a Few Decades

Plasma donation induces a beneficial protein expression profile shift in circulating human blood – Rob Flickenger-Commercial plasma donation yields a change in protein concentration similar to that observed in therapeutic plasma exchange (TPE) in humans. The post-donation expression profile shows an increase in many proteins after even a single donation, and the effect is enhanced with additional donations. Unlike TPE, human plasma donation returns saline without albumin to the donor, thus eliminating supplemental albumin as a contributing factor. The observed fold change falls outside the variation expected by natural circadian expression changes. N=6 humans (four donors, one monthly control and one circadian test). Seventeen antibody tests were performed, measuring the concentration of 507 proteins for each test. Full paper