SUBJ: Pentadecanoic Acid may be on par with rapamycin and metformin to increase healthspan.
SUBtitle: Drink only whole milk, not skim or 2%
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This newsletter is coming early. I am turning in my 2008 computer to buy a new one Friday, thanks to income from subscribers to my newsletter. The old one is obsolete and will not run the operating system issued 3 years ago. I am thankful for all my readers, especially my subscribers. Have a grateful Thanksgiving. Gratitude is useful to extend your healthspan, and perhaps more fulfilling than turkey.
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SHORT NOTES:
Pentadecanoic Acid (C15:0), its longevity benefits may be on par with rapamycin and metformin. The evidence is overwhelming to me.
Despite the drop in whole fat milk intake, the global prevalence of obesity, type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease increased. It turns out only whole milk fat has pentadecanoic acid that protects health.
Physical activity may partially buffer the adverse effects of sarcopenia on cognitive impairment.
SAMe required to manage 1 carbon metabolism. Otherwise, formaldehyde becomes a toxic substance in your body, damaging histones and DNA methylation.
Long-term relief from migraines by Nerivio Remote Electrical Neuromodulation (REN) device.
The Mediterranean, keto, and plant-based diets reduce cancer risk and progression.
How and why cells transfer mitochondria to one another to be more resilient.
Studies demonstrate the benefit of olive oil consumption on cognitive functions in people over 55.
Lifestyle interventions, such as exercise, healthy diet, and good sleep, can reduce cellular senescence.
LONG NOTES:
Pentadecanoic acid is ASTOUNDING. Please read this article. Over the past 40 years, diets with lower saturated fats have been recommended to decrease cholesterol levels and subsequent risks of heart disease1. In the U.S., during the 20-year period following this initial recommendation, the average individual’s daily intake of whole fat milk was reduced more than 4-fold, from 283 to 65 grams per day, in an effort to lower dietary saturated fats2,3. Despite this drop in whole fat milk intake, the global prevalence of obesity, type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease has increased4,5,6. Further, an 18-year longitudinal study including over 25,000 individuals demonstrated that children fed whole fat milk had a lower risk of having obesity compared to children who were provided fat-free or 1% fat milk, and multiple studies have demonstrated associations between higher dietary intake of full-fat dairy and reduced risk of type 2 diabetes and cardiovascular disease7,8,9. As such, there is a need re-evaluate potential health risks versus benefits of dietary dairy fats. IT TURNS OUT THE DIFFERENCE IS WHOLE MILK HAS PENTADECANOIC ACID.
I have just ordered a 90 day supply of this supplement, the only place I believe it is available. 90 days costs about $120. But it is much cheaper than metformin or rapamycin, safer, but with the same health effects. Order at fatty15.com/ALFREDORDMAN
In rats, an effective oral dosage is 5mg/kg, and much higher doses were absolutely safe. As people weight 60-80 kg, a dosage of 400 mg per day would be valid.
From GRG: Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds
I’ve been taking a supplement called “fatty15” for about 2 years now, before I was aware of potential longevity benefits. A new paper claims that its longevity benefits may be on par with rapamycin and metformin. Those 2 medications require a prescription. But pentadecanoic acid is a supplement.
The results of the study suggest physical activity may partially buffer the adverse effects of sarcopenia on cognitive impairment among the older adults in nursing homes. Accordingly, engagement in physical activity can help to preserve cognitive function among those with sarcopenia.
Science 3 Nov pg 532-SAMe important to manage 1 carbon metabolism. Its level drops substantially after puberty and must be taken as a supplement to maintain health. Otherwise, formaldehyde becomes a toxic substance in your body, damaging histones and DNA methylation.
Long-term relief from migraines. (TY Atid-EDI) Israel’s Theranica (see here previously) has reported successful long-term use of its Nerivio Remote Electrical Neuromodulation (REN) device for 409 migraine sufferers in the US. It consistently gave pain relief, functional disability relief and freedom.
A new review summarizes what we know about the Mediterranean, keto, and plant-based diets and their effects on cancer risk and progression [1]. Diet matters Since the War on Cancer began in the early 1970s, science has made giant strides.
In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient.
In this review, the researchers analyzed clinical trials, cohort studies, and cross-sectional studies to demonstrate the benefit of olive oil consumption on cognitive functions in people over 55.
A new review summarizes our knowledge about lifestyle interventions, such as exercise, healthy diet, and good sleep, that can possibly reduce cellular senescence [1].
