SUBJ: Americans don’t get enough magnesium

SUBtitle: yoga or aerobic exercise improve verbal fluency

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SHORT NOTES: Almost half of Americans don’t get enough magnesium from their diet;

Participation in yoga or aerobic exercise was associated with estimated improvements in verbal fluency; consumption of sugar-sweetened beverages and artificially-sweetened beverages associated with higher risk of dementia; Sugar-sweetened beverages (SSBs) providing excess energy increase adiposity; Adherence to lifestyle recommendations after non-muscle invasive bladder cancer diagnosis reduces the risk of recurrence [as does my Mito-C]; Diets enriched with protein and UFAs have beneficial long-term effects on liver fat, lipid metabolism and weight loss in adherent older subjects; This is scary. There is no suitable multivitamins for pregnant women!; pancreatic cancer spreads (metastasis) due to reduced levels of the RNA controlling protein RBFOX2;  Bacteria in the gut microbiome affect the body’s response to cancer immunotherapy (so keep microbiome healthy by eating some yogurt daily); The intestinal mucosa is a prime example of the decline in regenerative capacity, increase in cellular damage and metabolic dysregulation that characterizes – two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of intestinal stem cells [1] in mice; Exposing infants to pets likely reduces allergies to foods;  Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail. [My supplement creation Mito-C should also help prevent these problems.]; Four Warning Sign That Could Mean Bladder Cancer. 1. Invisible blood in your urine. 2. Visible blood in your urine.  3. Problems with urination. 4. Pain.

LONG NOTES:
Almost half of Americans don’t get enough magnesium from their diet. low levels of the mineral may set the stage for a variety of health issues, including type 2 diabetes, high blood pressure, and migraines. it may also protect against bone loss, broken bones, and the bone disease osteoporosis. Fights Inflammation. Magnesium helps your heart pump blood. Prevents Migraines. Lowers Odds of Diabetes. Source: Nuts and Seeds, whole grains, avocado, Dark Leafy Greens, Soy, Beans

Participation in yoga or aerobic exercise was associated with estimated improvements in verbal fluency compared to a non-active control group. Yoga and aerobic exercise may be promising approaches by which to promote cognitive function among older adults.
AJCN Apr, 23- Higher consumption of sugar-sweetened beverages and artificially-sweetened beverages associated with higher risk of dementia, and moderate natural juice intake was associated with a lower risk of dementia.

AJCN Apr, 23- Adherence to lifestyle recommendations after non-muscle invasive bladder cancer diagnosis and risk of recurrence.   (This is the cancer I had, and Triumph supplement I developed prevented recurrence.) The standardized 2018 WCRF/AICR score was constructed based on recommendations for body weight, physical activity, diet, and alcohol intake.

AJCN Apr, 23- Sugar-sweetened beverages (SSBs) providing excess energy increase adiposity.   The evidence provides a good indication that excess energy from sugars (particularly SSBs at high doses ≥20%E or 100 g/d) increase adiposity, whereas their removal decrease adiposity. Most other food sources had no effect, with some showing decreases (particularly fruits at lower doses ≤10%E or 50 g/d).

AJCN Apr, 23- Short-term trials indicate improvement of intrahepatic lipids (IHLs) and metabolism by dietary protein or unsaturated fatty acids (UFAs) beyond weight loss. We aimed to assess the effect of a dietary intervention high in protein and UFAs on IHLs and metabolic outcome after 12 mo, as long-term effects of such a combined intervention are unknown. Diets enriched with protein and UFAs have beneficial long-term effects on liver fat and lipid metabolism in adherent older subjects.

AJCN Apr, 23- This is scary. No suitable multivitamins for pregnant women! Most pregnant women in the United States (US) are at risk of inadequate intake of key nutrients during pregnancy from foods alone. Almost no US dietary supplements provide key nutrients in the doses needed for pregnant women. Affordable and convenient products that fill the gap between food-based intake and estimated requirements of pregnancy without inducing excess intake are needed to support pregnant women and their offspring.

An international study let by Hebrew University researchers has discovered that pancreatic cancer spreads (metastasis) due to reduced levels of the RNA controlling protein RBFOX2. The finding provides a new target for pancreatic cancer treatments.

Bacteria in the gut microbiome affect the body’s response to cancer immunotherapy (see also here previously). Also, patients treated with specific antibiotics had a poor response to CAR-T cancer treatment.

The intestinal mucosa is a prime example of the decline in regenerative capacity, increase in cellular damage and metabolic dysregulation that characterizes aging (Di Giosia et al., 2022). These changes are linked to age-associated intestinal disorders, with aging also a major risk factor for colorectal cancer (CRC). In a new study published in Aging Cell, researchers have shown that two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of intestinal stem cells [1] in mice.

Economist 4/1/23 pg 65-Exposing infants to pets likely reduces allergies to foods. Of 66,000 kids, 22% born in households with pets, those with dogs less allergic to eggs, milk, and nuts; with cats less allergic to eggs, wheat, and soy.

Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail. [My supplement creation Mito-C should also help prevent these problems.] Aging coincides with the accumulation of senescent cells within skeletal muscle that produce inflammatory products, known as the senescence-associated secretory phenotype.   These data support that MET+LEU has skeletal muscle cell-autonomous properties to prevent atrophy by reversing senescence and improving proteostasis. (I envy those who take metformin.)

Four Warning Sign That Could Mean Bladder Cancer. 1. Invisible blood in your urine. 2. Visible blood in your urine.  3. Problems with urination. 4. Pain.